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For every movement of stock in the SAP system there is a movement type, which represents the inventory movement For example, a movement of stock between plants has a movement type which is different from the movement of stock for a customer sale, which in turn is different from the movement type for receipt of stock for a customer return This field indicates which SAP inventory movement to use for schedule line category CP CP is assigned to item category TAN, which is a standard item category representative of a material to be sold to a customer The goods movement is a movement from our stock as a sale to our customer It would be correct to leave this field blank for items for which no stock movement happens Likewise, should this schedule line be assigned to a return item category, you should ensure the movement type here is relevant for returns, such as a goods receipt The movement type 1-step is used when two goods movements need to happen for a schedule line category for example, in a stock transfer (the issue of stock from one plant and another movement for the receipt of the stock into another plant) The order type is the assignment of the purchase requisition type to the schedule line, which allows the system to automatically create a purchase requisition for this schedule line category This is used for third-party sales for example, if the customer places the order with you, but you need to buy the material from your supplier for delivery to the customer The system can automatically create the purchase requisition to purchase the material from the supplier

ointment, 625 25 mg applied two to four times daily; and transdermal nitroglycerin patches that deliver nitroglycerin at a predetermined rate (usually 5 20 mg/24 h) The main limitation to long-term nitrate therapy is tolerance, which occurs to some degree in most patients The degree of tolerance can be limited by using a regimen that includes a minimum 8- to 10-hour period per day without nitrates Isosorbide dinitrate can be given three times daily, with the last dose after dinner, or longer-acting isosorbide mononitrate once daily Transdermal nitrate preparations should be removed overnight in most patients Nitrate therapy is often limited by headache Other side effects include nausea, light-headedness, and hypotension 4 -Blockers -Blockers prevent angina by reducing myocardial oxygen requirements during exertion and stress This is accomplished by reducing the heart rate, myocardial contractility, and, to a lesser extent, BP The -blockers are the only antianginal agents that have been demonstrated to prolong life in patients with coronary disease (post-myocardial infarction) They are at least as effective at relieving angina as alternative agents in studies employing exercise testing, ambulatory monitoring, and symptom assessment -Blockers should be considered for first-line therapy in most patients with chronic angina -Blockers with intrinsic sympathomimetic activity, such as pindolol, are less desirable because they may exacerbate angina in some individuals and have not been effective in secondary prevention trials The pharmacology and side effects of the -blockers are discussed in 11 (see Table 11 7) The dosages of all these drugs when given for angina are similar The major contraindications are severe bronchospastic disease, bradyarrhythmias, and decompensated heart failure 5 Calcium channel blocking agents Verapamil, diltiazem, and the dihydropyridine group of calcium blockers are chemically and pharmacologically heterogeneous agents that prevent angina by reducing myocardial oxygen requirements and by inducing coronary artery vasodilation Unlike the -blockers, calcium channel blockers have not been shown to reduce mortality postinfarction and in some cases have increased ischemia and mortality rates This appears to be the case with some dihydropyridines and with diltiazem and verapamil in patients with clinical heart failure or moderate to severe LV dysfunction Metaanalyses have suggested that short-acting nifedipine in moderate to high doses causes an increase in mortality It is uncertain whether these findings are relevant to longeracting dihydropyridines Nevertheless, considering the uncertainties and the lack of demonstrated favorable effect on outcomes, calcium channel blockers should be considered third-line anti-ischemic drugs in the postinfarction patient Similarly, with the exception of amlodipine, which in the PRAISE trial proved safe in patients with heart failure, these agents should be avoided in patients with CHF or low EFs The pharmacologic effects and side effects of the calcium channel blockers are discussed in 11 and summarized in Table 11 9 Diltiazem and verapamil are preferable because they produce less reflex tachycardia and.

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Time in minutes on Bruce protocol 4 % angina index (0 = no angina on test; 1 = angina, not limiting; 2 = limiting angina) Total Score 5 10 to +4 11 = ____________________ = Total score

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